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Hyperbaric Oxygen
WHAT IS HYPERBARIC OXYGENATION THERAPY?
hyperbaric oxygenation (HBO) therapy is the inhalation of oxygen (O2), late dose (saturation approaches 100%) for short periods and under pressure inside a fully pressurized chamber (above 1.5 atmospheres). This form of medical treatment is indicated for a number of very well-defined diseases. Importantly, the physical, physiological and biochemical obtained by chemotherapy, are due to saturation of oxygen at high pressure, the hyperbaric chamber is only the means used to grant it, because otherwise the treatment environment could not comply. Topical administration of oxygen in an isolated area of \u200b\u200bthe body or limbs, no is hyperbaric oxygen.
WHAT ARE THE EFFECTS? The main effects of this therapy are:
HYPEROXYGENATION (extra oxygen saturation): The high pressure saturated with oxygen in a 2,000% over the patient's blood. This high saturation dose helps to regenerate tissue damaged by burns, cuts, or diseases that can cause oxygen deficiency in certain organs of the body, such as those that cause circulatory compromise (poor circulation), such as diabetes, or by damage to blood vessels. The tissue regeneration or healing process needed to effectively carry oxygen. With poor oxygenation process is delayed or impossible. With Hyperoxygenation be largely remedied the problems of lack of oxygen caused by defects in the circulation, edema, or any other cause. Hyperoxygenation sweeping also helps other gases and is why it is useful in the treatment of poisoning by toxic gases.
NEOVASCULARIZATION (regeneration and creation of new blood vessels) Hyperoxygenation provided by this therapy increases the growth of new blood capillaries and regeneration of existing ones. These vessels are the latest in the chain of the human body circulation and come into the body of oxygen and nutrients it needs to continue living, instrumental in the healing process and tissue repair committed under the influence of infections, radiation, cancer, aging and arterial or varicose ulcers. OSTEOGENESIS (bone regeneration): Due to the HYPEROXYGENATION produced by this therapy, the cells get all the oxygen required for the remodeling of the bones that fracture is affected by aging, softening or infections caused by pathogens. ANTIMICROBIAL (elimination of germs that cause infections): supplied Hyperoxygenation the white blood cells the oxygen they need to defend the body from bacteria. Also for more effective operation of some antibiotics that require high levels of oxygen in the tissues. Oxygen itself is able to directly destroy some bacteria, mainly the anaerobes. So that it acts in synergy (sum), with the individual's immune system, in addition to its bactericidal action. WHAT ARE THE MECHANISMS OF ACTION OF HYPERBARIC OXYGENATION ON OUR BODIES?
In the CENTRAL NERVOUS SYSTEM:
• Create paradoxical vasoconstriction during HBO vasodilation followed by post-HBO. (It has been determined vasodilation in infarcted areas, thus improving circulation.) • Increases permeability the blood-brain barrier. • Stops or reduces the production of edema in the central nervous system. • Improves microcirculation • O2 Increases in spinal fluid. • Evidence of axonal regeneration.
in the circulatory system:
• Anti-platelet aggregating. • Increases old red blood cell hemolysis. • Reduce cardiac work. • Increases resistance to cardiogenic shock.
the endocrine system:
• Stimulates the endocrine glands and thymus. • Decreases insulin requirements. • Increased complement activity. (Immune activator). • Improves metabolism.
the gastrointestinal system:
• Decreases gastric acid secretion. (Reduce the gastritis and ulcers) • Lower the tone of the pylorus. (Improved gastric emptying). • Lower levels of norepinephrine and monoamixidasa in the liver. • Increases intestinal motility.
IN GENERAL:
• Move other gases. • Follow the Law of Mass Action. • Creates a marked increase in the partial pressure of oxygen in the arterial (PaO2), but little change in the Partial Pressure of Oxygen venous circulation (pvO2). • Raise the oxygen in the tissues for a long time after HBO exposure. • Increased oxygen tension in blood, urine and total body fluid. (Henry's Law). • Regulates collagen deposition. • Increases bone cell activity. • Free Radicals. Hyperbaric oxygen therapy increases levels of superoxide dismutase (SOD), glutathione and catalase which are natural antioxidants that protect us from free radicals, factors that damage our cells. • As Preventive Medicine. Based on the above arguments, not only hyperbaric oxygen is indicated for patients with certain disease, but can be used by all people with the purpose of revitalizing all organs and thus prevent disease, prolong stay healthy and quality life. Remember that HBO is actually a normalizing and regulating all biological functions: it raises the immune system, tones the skin, prevents or corrects the hypoxia, in general, is the underlying factor of almost all diseases. "• Hyperbaric oxygen therapy increases up to 8 times the circulating stem cells in the body as shown by the study by the University of Pennsylvania (USA) published in the online edition of 'American Journal of Physiology-Heart and Circulation Physiology' November 18, 2005.
WHAT FOR DISEASE TREATMENT SPECIFICALLY STATED THIS?
hyperbaric oxygenation (HBO) is currently the primary therapy for decompression sickness, Enbolismo Gaseous, carbon monoxide poisoning and organic solvents, gas gangrene and severe tissue damage from burns, lasceraciones and is used as a treatment traumastismos.También all those changes or situations which have been determined physiological basis for use and we have already mentioned.
WHERE THE THERAPEUTIC INDICATIONS ARE FROM ABOVE?
The text above is a summary of the information most commonly used for hyperbaric oxygen contained indications of: American College of Hyperbaric Medicine, Medical Research Society French Society of Hyperbaric Medicine China, Japan Society for Hyperbaric Medicine, Hyperbaric Medical Society (USA), Ministry of Health of the former USSR, Moscow and Sociedad Venezolana de Medicina Hiperbárica.Se international conferences have been conducted at the Universities of Amsterdam, Glasgow, Duke, Sapporo, Vancouver, Aberdeen, Moscow, California, Long Beach, among others. Currently, the Society of Underwater and Hyperbaric Medicine in the United States of America, founded on November 25, 1976 and domiciled in Bethesda, Maryland, has 2,000 members and 2,005 international approximately 900 hyperbaric chambers operating in USA. SITUATIONS IN THE TREATMENT contraindicated Hyperbaric Medicine
In people who have any of the following conditions is contraindicated: pneumothorax, pulmonary emphysema, epilepsy, Cold upper airway.
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Hyperbaric Medicine: Improving Health 100% pure oxygen
Today we are more concerned about climate change and global warming, situations that affect our planet and are undoubtedly very important, but at the same time we are losing view which is also very important as the polluted air we breathe, the demineralization of our soils and pollution of our waters coupled with the stress of today's busy lifestyle we live, very significantly harm our body causing toxins that fill us weaken us and make our immune system is not functioning effectively and properly. Currently
not acquire the amount of oxygen necessary because although we will capture 20% of it, the body is a beautiful temple made of millions of those cells feed on oxygen, an oxygenated body is a healthy body, a body Toxic does not receive oxygen to release toxins is a breeding ground for diseases of all kinds such as, bacterial, degenerative, infectious and viral diseases. To properly oxygenate the body to detoxify everything you eat take or will work better in our bodies and our cells are oxygen and clean.
100% pure oxygen is the key to the Hyperbaric Medicine which has applications in various diseases, injury rehabilitation, improvement of the immune system as well as tone the skin preventing disease and prolonging life.
Hyperbaric Medicine in Mexico and the world began to attract attention when he said Michael Jackson, Fidel Castro and even the Pope John Paul II used to be their oxygen therapy in a special chamber called a hyperbaric chamber and also some high-level athletes do the same to recover from serious injuries.
The truth is that you have data from 1662 of hyperbaric treatment (hyper = increase, barium = pressure), which relate the first tests carried out by a British physician named Henshaw to improve seriously injured. The so-called "air baths" were popularized in the nineteenth century throughout Europe and led U.S. patients. In America, the first hyperbaric chamber was built in Canada in 1860, for treatment of nervous disorders.
In the last century NASA (United States Agency for Research in Aeronautics and Space) studied the oxygen in the fields of aviation and marine diving, which went beyond the scientific community giving rise to the foundation in 1967 of the Undersea and Hyperbaric Medical Society ( Undersea and Hyperbaric Medical Society) thus increased its therapeutic applications.
hyperbaric oxygenation (HBO) is a treatment which consists of patient breathing 100% oxygen at a pressure above 1.5 atmospheres absolute (air is the unit of measure of pressure). Oxygen is supplied in specialized handling equipment, which are called hyperbaric chambers, which is equivalent to the pressure that is supported in water deeper than 5 meters. so that helps to raise large amounts of oxygen to dissolve in the blood and other tissue fluids (10 to 15 times more), which makes the vital gas to all parts of the body, especially to those areas affected by injury or disease.
Oxygen is the main element of life that is why the Hyperbaric Medicine is an adjunct in the treatment of various diseases such as (diabetes, diabetic foot, arthritis, varicose veins, migraine, multiple sclerosis, stroke, ulcers, stress, injuries radiation therapy, impotence, stomach problems, Parkinson's disease, wound healing, atherosclerosis, bone grafting, stroke, psoriasis, rheumatoid arthritis, myocardial infarction, idiopathic sudden deafness and acoustic trauma, insomnia, and many more) but other your application is in sports practices helping the consolidation of fractures, sprains, injuries and reducing recovery time and increase muscle mass without anabolic toxins and it is not enough also stimulates new natural collagen skin moisturizing and preventing it from oxidation and reduces the damage that free radicals produced and that activate the body's natural defenses, so that delays aging, the cells regenerate, improves blood circulation reducing cellulite, reduce skin blemishes, improves skin and helps reduce wrinkles, is recommended to patients undergoing reconstructive plastic surgery because it reduces recovery time by 50% and many more benefits.
hyperbaric oxygenation has a physiological explanation:
normally breathe through the nose, lungs saturated with oxygen via hemoglobin and doing an exchange in the alveoli. But inside the camera that way of breathing is in the background as each cubic centimeter of oxygen you breathe through your nose, the skin by osmosis absorbs about 50 and that oxygen is deposited in vital fluids saturating the body and slowly producing multiple beneficial effects.
Nowadays, thanks to technology these therapies and can be taken in the comfort of your home or office, providing patients and bringing this important treatment Biobaric pioneer in the delivery service and that is always thinking about welfare and comfort of its patients are at your service with cutting edge equipment and professional staff fully 100% qualified, willing to grant you the best and warmest services.
not hesitate and treat yourself to a little life, visit www.biobaric.com.mx and make an appointment in eduardo@biobaric.com.mx for more technical information visit our blog at http:// biobaric.blogspot.com or we can answer your questions instantly online in our meseenger www.biobaric @ live.com.mx our phones are finally 0445518930751 53082522 or where will gladly assist you.
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100% pure oxygen is the key to this variant of Medicine, which has applications in various diseases, injury rehabilitation, to tone the skin and even improve the immune system and, thus, prevent disease and prolong life.
Even without much coverage in Mexico as in other countries, hyperbaric medicine began to attract worldwide attention when he said that Michael Jackson turned to her to slow aging, remember? Later it was learned that Fidel Castro and even Pope John Paul II often occur bathroom oxygen in a special camera that meets this purpose, and that some top athletes do the same to recover from serious injuries.
The truth is that you have data from 1662 of hyperbaric treatment (hyper = increase, barium = pressure), which relate the first tests carried out by a British physician named Henshaw to improve seriously injured. The so-called "Air baths" were popularized in the nineteenth century Europe and led by U.S. patients. In America, the first hyperbaric chamber was built in Canada in 1860, for treatment of nervous disorders.
Already in this century, NASA (U.S. agency for research in aeronautics and space) was entered in the study of oxygen in the fields of aviation and marine diving, which went beyond the scientific community, including medicine - which led to the founding of the Undersea and Hyperbaric Medical Society (Undersea and Hyperbaric Medical Society) in 1967, thereby increasing their therapeutic applications.
The so-called hyperbaric oxygen therapy is a method that involves making the patient breathe 100% oxygen at a pressure between 1.5 to 3 atmospheres absolute (ATA), equivalent to the pressure that rests on the water to a depth of between 5 and 20 meters. To put in other words, natural atmospheric pressure at sea level is 14.7 pounds per square inch (760 mm hg)-equivalent to one atmosphere absolute (ATA) - so that the rise to 2 or 3 times more aid to large amounts of oxygen to dissolve in the blood and other tissue fluids (10 to 15 times more), which makes the gas is vital to all body parts especially those areas affected by injury or disease.
Oxygen is supplied through masks installed inside a capsule called a hyperbaric chamber, which is an airtight container built with welded steel plates, often cylindrical, with a number of systems and accessories that allow the controlled increase of pressure, for some t iene the appearance of a spaceship.
Who recommended?
Hyperbaric Medicine has more applications, some surprising, with encouraging results. For example, one of the main effects of increased oxygen (Hyperoxia) is to mitigate the damage from the toxins that naturally oxidants lead to aging of cells, if we add the fact of increased production of collagen (the substance that gives the skin Firmazo), the aesthetic effects are amazing .
Moreover, hyperbaric oxygenation bone regeneration (osteogenesis) in fractures or osteoporosis (become porous and weak) and fixes the tissue hypoxic states, ie, carries oxygen to tissues throughout the body, which collaborates reduce inflammation, accelerate the healing process from minor burns or injury, to graft and reimplantation of limbs, and even in the reconstitution radiation-damaged tissue, gangrene or necrotizing infections in which a flesh-eating bacteria, it is noteworthy that the restoration of tissue includes tissue located in the gastrointestinal area (gastric ulcer).
also activates the body's natural defenses (immune system), which is reflected in the rapid recovery from infectious processes or as few of them.
also hyperbaric oxygen inhibits the development of rheumatoid arthritis (inflammation of the tissue that lines the joints) because it can suppress swelling, have better results if prescribed for treatment in stages the problem early.
addition, having the brain more oxygen significantly improve concentration and memory. It also reduces inflammation anywhere in the body or neurons, and prevents blood clots by making it cleaner and lighter.
is important to note what happens in cases of cerebral palsy, and it is an injury to a part of the brain usually associated with premature birth, with poor circulation or low oxygen activity, and those who suffer from this problem improve your bass tone muscles (hypertonia).
also worth noting that MS is a disease central nervous system that affects the brain and spinal cord, which have nerve fibers that are wrapped and protected by myelin, a substance that facilitates the conduction of electrical impulses between them. If it is destroyed or damaged electrical communication, and from the brain is interrupted, the Hyperbaric Medicine creates a favorable environment for the repair of myelin, while reducing the overactive immune system that is causing damage to the substance .
Several studies have shown that 90% of migraine patients experience complete pain relief when treated for at least 10 sessions. The patient with diabetes also get positive results when undergoing hyperbaric medicine, as it increases your immune defenses, active insulin, stimulates healing (which is difficult in these patients) and improves blood circulation.
Moreover, a common problem among those who practice diving is the air intake on blood vessels (called air embolism), although complications often occur in medical procedures. Usually there are no consequences if the air is in a vein, but when it lodges in an artery can block blood flow, which is of serious consequences, for example, if one of these bubbles are in a brain artery can lead to stroke or death. Then, hyperbaric oxygen therapy works by removing nitrogen (can have toxic effects) of the bubble, plus it reduces the size of it.
facial palsy (or Bell) is characterized by the sudden weakness of one side of the face, which is usually treated with a derivative of cortisone (steroids) to reduce swelling of nerves involving facial movement . Recent studies have shown that hyperbaric oxygen is more effective than anti-inflammatory drugs, both to shorten the duration of the disease and to increase the probability total recovery.
Psoriasis is an inflammatory skin disease characterized by frequent episodes of redness, peeling and itching that can occur suddenly or gradually and can affect any age but usually starts between 15 and 35. The use of hyperbaric oxygenation treatment has shown that high percentage of patients experience a very noticeable recovery after 10 sessions.
These are just some examples of the results that the use of hyperbaric oxygen provides the body. Before
In Mexico, the Hyperbaric Medicine is used in important health sector institutions such as the Mexican Social Security Institute and the Institute for Social Security Service for State Workers, among others, as well as private clinics.
As stated previously, oxygen is delivered to the patient through a special camera, but before joining must meet certain provisions, like getting 100% cotton clothes, no accessories or metal objects, fragrance, creams and / or makeup of any kind on the body. A session is usually prescribed daily-which has a duration of 50 minutes on average, "although each disease has its own treatment regimen, which includes parameters as system pressure, exposure time and number of sessions.
Once or patients (there are cameras that can accommodate up to 25 people seated), are prepared, the device conforms to the pressure indicating treatment, it is worth reiterating that breathing pure oxygen using airtight masks or helmets designed for this purpose. The patient is always accompanied by trained and qualified to address any eventuality.
side effects are minimal, the most common feeling of fullness in the ears, similar to that experienced during a flight or to climb a mountain, " which is presented to compensate for the pressure in the organ of hearing, these annoyances can be solved by chewing gum or yawning. We should note that access to the hyperbaric chamber will be restricted to those with claustrophobia, ie exaggerated fear of enclosed spaces, which can alter emotional stability.
Finally, note that hyperbaric medicine is often part of comprehensive treatment of certain conditions, for example, recovery from surgery or in processes that require prolonged attention, such as osteoporosis.
science again surprising, is not it? If it is interest following a hyperbaric oxygen treatment which is recommended saludymedicinas.com.mx advice from professionals in the field, so as not to risk time, money and, especially, health. Raul Serrano
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Benefits of oxygenation and its effects on the body.
1.-Relaxation: A state in which you feel calm, serene, peace and general welfare.
2.-Energizing: Increased energy, focus and alert.
3.-domestic happiness: good humor, kindness.
4.-Floating: It seems to come upstairs to another level of energy, as if your body weight is significantly reduced.
5.-promotes cell reproduction and regeneration
The human body is composed of something like 1000 trillion cells, far more than all the stars that make up nuesra Galaxy. In all these cells 600.000 million die every day being replaced by an equal number. That is, every second our body regenerates more than 10 million cells. A normal skin cell lives only two weeks ago, those of the bones are renewed every three months. Every 90 sec. Millions of antibodies are synthesized, each with about 1200 amino acids, and each time is 200 million red blood cells regenerate.
The air we breathe normally consists of 78% nitrogen and 21% oxygen by volume. The other gases together, called trace gases, are the 1% These are argon, carbon dioxide. Neon, helium, hydrogen and xenon. The level of impurities varies according to geographical location or proximity to industrial areas or heavy traffic highways.
BENEFITS OF OXYGENATION.
(cellular oxygenation)
THE OXYGEN treat, cure and eradicate MOST diseases, disorders, aches and HEALTH PROBLEMS.
a polluted environment prevents adequate cell regeneration, MUST BE THE OXYGEN.
BENEFITS OF OXYGEN
* PAR CELL BOOST PLAY THE AUTO BODY CAN heal.
* IMPROVED IMMUNE SYSTEM AND THE NERVOUS SYSTEM.
* REDUCE BLOOD PRESSURE AND MYOCARDIAL risky.
* IMPROVEMENT Diabetic conditions.
* Accelerates Wound Healing in Diabetic Patients.
* IMPROVING THE PERFORMANCE OF ALL THE BODIES.
* INCREASE ENERGY (oxygen DELIVERS 90% OF THE ENERGY BODY, FOOD THE REMAINING 10%)
* MEMORY IMPROVEMENT
* Reduces the appearance of varicose veins and cellulite.
* Improves digestion and METABOLIC WORK.
* REDUCES FATIGUE. Improves relaxation and natural sleep.
* REDUCE THE CONCENTRATION OF FAT. Improves mental relaxation.
* Enhances physical performance.
* ES A NATURAL REMEDY FOR HEADACHES, MIGRAINE AND SURF.
* INCREASED MELANIN PRODUCTION.
* STRENGTHENS THE HAIR AND IMPROVING THE SOFT SKIN.
* quickly replenish the body's energy.
* helps filter toxins from the blood.
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Coronado Dr. Jose M. Bernardo Physician and Surgeon
Hyperbaric Medical Director, SA
* Our Lady of Pilar Sanatorium
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01015 - 2279 Tel Guatemala
5000 x 624, 55182472 Emergency
Dr. Luis Angel Hernández
Surgeon Maxillofacial
* Dental Group
Guatemala
9 ª. Calle 2-81 zona 14 01014
- Guatemala
PBX
2367 5929 5600 9132
Emergency
* Our Lady of Pilar Sanatorium
3 rd. Street 10-71 zone 15
01015 - Guatemala
INTRODUCTION GENERAL HISTORICAL
SCIENTIFIC COMMUNITIES CONCEPT OF PHYSIOLOGICAL EFFECTS O2Hb
CELLULAR AND BIOCHEMICAL EFFECT
ANTI-EDEMA EFFECT
IN CHRONIC REFRACTORY OSTEOMYELITIS
EFFECT ON OSTEO-radionecrosis EFFECT ON GRAFT
Summary REFERENCES
INTRODUCTION
Jaw Region and oral health is a constant concern in any individual who seeks to stay healthy. The manifestations of illness dentogingivales, particu-larly those with inflammatory edema, are a frequent complaint, although large facial deformities from odontogenic abscesses and less so in urban areas. In any case, whenever there is an event that alters the system-Natica Estomatog, patient consultation, especially to relieve pain and restore the morphology normal facial. Additionally, all injuries, which involve the facial region are of great concern to patients and professionals, although in severe cases of multiple trauma, are the last to be resolved. At the right time, always made all efforts to rehabilitate the damaged parts of the face. The type of treatment is very important for the restoration of normal function and prevent facial deformity. A modern therapeutic method used in the management of facial trauma caused by different causes (traffic accidents, firearm, a short, aggression, etc.), as well as dental infections severe, refractory osteomyelitis and osteo-radionecrosis, is the use of hyperbaric oxygen therapy (O 2 Hb), with which the results are very effective, improving the speed and quality of healing tissue, shortening recovery time.
The O2Hb is a branch of the Hyperbaric Medicine. Therapeutic use SIVO non-invasive, is based on an increase in the capacity of diffusion and oxygen tension in the plasma. Oxygen breathing 100% pure high ambient pressure conditions, within a tight team called hyperbaric chamber, it generates multiple biochemical effects, physical and physiological positive.
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GENERAL
The Earth's Atmosphere normally exerts a surface pressure of 14.7 pounds per square inch or 760 millimeters of mercury (mmHg.) at sea level, being equivalent to one atmosphere absolute (ATA). This atmosphere we breathe is a gaseous mixture (air), which is composed of 21% oxygen and approximately 79% of nitrogen in normal conditions. During the session O2Hb pressure inside the chamber is increased two to three times the equivalent of atmospheric pressure, so that breathing oxygen at 3 ATA, Oxygen pressure values \u200b\u200bat the level of pulmonary alveoli amounted to 2.173 mmHg, the partial pressure of arterial oxygen (PaO2) to 1.800 mmHg rise in venous blood levels reaches 200 to 300 mm Hg, hemoglobin is saturated at 100% ability, diffusion distance is increased 8 times and while in normal plasma 0.3 vol/100 carries with O2Hb vol/100 rises to 6.6 (20 times).
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HISTORICAL
Although scientific-based applications cally in hyperbaric technology are newly developed, the use of compressed air has ancient roots as described Hensaw British physician (1662), long before the oxygen was identified as an individual. The doctor realized that the large increase in air pressure could ease some serious injuries. He built a camera which he called "home", whose function was the administration of air at different pressures for him treating various chronic diseases.
Use of Oxygen for medical problems initially reported by Beddoes (1794). The first article of the use of oxygen under pressure (hyperbaric oxygen) as adjunctive therapy was described by the French surgeon Fontaine in 1879. In Latin The first hyperbaric chamber was built in Canada in 1860, a year later in New York, for treatment of nervous disorders. In 1939, Albert Behnke reported the first clinical use O2Hb to treat decompression sickness. In the decades around the years 1950-60 they began to lay the physiological bases O2Hb, demonstrating that it is capable of combat tir anaerobic bacteria infections and to improve tissue oxygenation in separately from the amount of hemoglobin. In 1960, Boerema, considered the father of modern Hyperbaric Medicine in its publication Life without Blood, tells the replacement of blood plasma in pigs, expanding pressure of oxygen air three times, all without apparent adverse effects observed, although hemoglobin levels of pigs was almost zero. In these same decades has accelerated the study of oxygen in the fields of aviation and marine diving, especially at NASA.
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SCIENTIFIC COMMUNITIES
Many countries have made scientific medical organizations dedicated to the investigation and treatment with hyperbaric oxygen. In 1967 he founded the Undersea and Hyperbaric Medical Society (UHMS) located in Maryland, which is responsible for the approval of medical conditions that respond to hyperbaric oxygen treatment. In 1976 he founded the Hyperbaric Oxygen Committed, an organization that is responsible for the ongoing review of new research and clinical applications, to issue recommendations on the subject of dealing with disorders O2Hb. Globally in 1988, created the regulatory agency International Society of Hyperbaric Medicine.
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O2Hb CONCEPT
Manage 100% pure oxygen under atmospheric pressure patients increased from 1.5 to 3 ATA in a hyperbaric chamber, carefully controlling the oxygen level and atmospheric pressure.
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PHYSIOLOGICAL EFFECTS.
The O2Hb combines two mechanisms: first, a high ambient pressure and the other, the respi-ration of 100% pure oxygen. This causes two effects: a volumetric effect and an effect solumétrico.
The volumetric effects due to increased environmental pressure and is based on Boyle's Law, which postulates that the human body, raising the ambient pressure is inversely proportional decreases in the volume all body cavities that are not in contact with the respiratory tract (bladder, digestive tract, ears, sinuses, etc.). This effect is reversible upon cessation of overpressure.
Solumétrico Effect is due to increased partial pressure of O2 and is based on Henry's Law which holds at the same temperature and increasing pressure, increases the dissolution of gas in a liquid, so that breathing 100% pure oxygen in a hyperbaric atmosphere, increases dissolved oxygen in the plasma after saturated hemoglobin.
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CELLULAR AND BIOCHEMICAL EFFECT
Oxygen is a chemical element with atomic number 8 and atomic weight 15.99, density is 1.105g/cm3. It has a diatomic molecule, but there is also the triatomic molecule. It is essential for the cells because the latter derive their energy for respiration, due to the ability of chemical bonds. Increased oxygen tension results in increased phagocytic activity of white blood cells, outlined as follows: polimorfonuclears leukocytes, neutrophils, eosinophils and mononuclear phagocytes represent the first and most important line of defense against microorganisms that are introduced into the body. Bacterial death usually has 2 phases: the 1 st. Degranu Phase-tion involves, in which the bacteria digested is exposed to various substances. The 2. Is the oxidative phase, which depends on molecular oxygen captured by the leukocyte. Under normal conditions, the phagocytic cell is at rest and a stimulus to produce the respiratory burst characterized by a dramatic increase in oxygen consumption, it generates highly toxic and arousal reduction of oxygen, oxygen-dependent microbicidal mechanisms (MMODE) , which is the set of changes to the metabolism of oxygen and takes place in phagocytes with a large number of soluble and particulate stimuli that alter their membranes, they are usually composed of inflammatory processes: opsonisados \u200b\u200bmicro-organisms, com-fragment of complement C5, oligopepetidos N-formylated bacterial, and leukotriene B4. Everything associated with increased glucose oxidation. It occurs as a result, highly toxic metabolites such as superoxide, hydrogen peroxide, hydroxyl radical and oxygen siguelete. The superoxide anion is formed by the univalent reduction of oxygen, ie the capture of an electron, by action of a membrane oxidase system of PMN, the NADPH oxidase. Superoxide anion undergoes spontaneously or by action of superoxide dismutase (SOD), a disproportionation reaction to form hydrogen peroxide, which for bond cleavage-OO-(peroxide) is highly oxidative oxygen species such as hydroxyl radical (O =). On the other hand myeloperoxidase catalyzes the reaction of hydrogen peroxide with chloride anion resulting in the anion hypochlorite, a powerful oxidant, from which lipophilic chloramines are generated highly toxic. All of these oxidants have high toxicity for different organisms that have low stress protection against oxygen. The absence or low concentrations of protective enzymes against oxidative effect (catalases, peroxidases) causes an increase in the partial pressure of oxygen in the environment surrounding this highly hostile environment for survival this type of bacteria.
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ANTI-EDEMA EFFECT
Inflammation is a general defensive response of all higher organisms, which has a protective nature and its purpose is to rid the body of the initial cause of tissue injury. After altering the tissue produces a disorder that explains their circulatory cardinal signs: Blush, Tumor, Calor, pain and impaired function. The key feature is the reaction of blood vessels (vasodilation), alterations of microvascular permeability (edema formation) and defense cell accumulation. In soft tissue trauma injuries occur that affect various tissues of a compartment or several compartments of an area or region. In all cases there is local hypoxia (PO2 drop mitochondrial critical level, 1 point or Pasteur mmHg) secondary to blood flow deficit due to injury or compression of vessels and reduced transport capacity. By using O2Hb, peripheral vasoconstriction occurs hyperbaric a physio-logical mechanism of defense against hyperoxia, and therefore only affects healthy tissues. When a local state of hypoxia (edema), this area benefits deprived plasma volume at the expense of healthy territories; ie, a phenomenon similar to known arterial steal in reverse, so that healthy tissue hypoxic tissue supercharging, Effect of Robin Hood. This effect is able to recover and overcome the pressure from 2 to 5 mm Hg, with which the EU-lula carried out a series of biochemical reactions important micas. In conclusion, the effects of trauma are O2Hb reverse tissue hypoxia, reduce swelling by vasoconstriction, by reducing blood flow (compensated by hyperoxia).
Oral Surgery extensive edema of mild to moderate O2Hb treatable. Maxillo-facial Surgery elective post-surgical benefits are explained by the mechanism O2Hb action. In severe facial injuries, the pre-surgical O2Hb may decrease the waiting time for reconstruction (usually wait until the swelling is resolved or controlled for surgery), shortening the time of hospitalization and ultimate recovery. In these patients, there is usually traumatic brain injury with varying degrees of cerebral edema (cytotoxic or vasogenic) appreciably improves the O2Hb. In face of traumatic events with accidental or surgical wounds may be blocking lymphatic return that prevents absorption of fluids and proteins that normally traffic exchange capillary (extracellular edema, increased fluid in the interstitial space).
Normally, lymph vessels of the forehead and the anterior region of the face accompanying facial and other vessels drain into the submandibular lymph nodes. The lymphatics of the lateral region of the face, including eyelids, drain inferiorly into the superficial parotid lymph nodes. At the same time they drain into the deep parotid lymph, which is to drain into the cervical linfonóudlos. The nodes of the upper lip and the side portions of the lower lip drains into the submandibular lymph nodes tubular, while the nodes in the central part of the lower lip and chin drain into the lifnonódulos submentoneanos, from which the lymph drains directly into the jugular lymph nodes omonioideos.
erythrocyte saturation with 100% oxygen in the pulmonary alveoli
Home of the respiratory chain in the leukocyte
traumagenic edema should be differentiated from other conditions in the region that bucomaxilofacial can also occur where the use of O2Hb may be considered and decided by the expert. There is increased capillary permeability in infections with extracellular edema, ischemia, burns, exposure to toxins, vitamin deficiency and immune response in lymph blockages CA, infections and surgery on lymphedema is swelling of part of the region face due to the accumulation of lymph in the tissues, mainly in the fat beneath the skin, as a result of problems in the lymphatic Sitema characterized by excessive accumulation of protein in tissue fluid (edema), chronic inflammation, thickening and scarring connective tissue; in Melkerson-Rosenthal syndrome consisting of recurrent swelling of the lips, intermittent facial paralysis and scrotal tongue.
clinical edema can also be the result of intracellular edema. The main causes are: decrease in cell metabolism and loss of proper cellular nutrition. This edema occurs in states of shock and others with compromised cardiac output. Decreased oxygen and nutritional supply in the cell results in depression of the cell's metabolic ability to pump out excess Na, this accumulation of intracellular Na H2O attracts inward.
intracellular edema in Inflammation usually occurs as a result of increased permeability induced by the inflammatory process. Typically, the highest concentration of oxygen and nutrients in the capillary plasma promotes the dissemination of these to the tissues where they are constantly consumed. In contrast, the high concentration of CO2 and waste products in tissues, promote the diffusion of it into the blood plasma in the veins. Therefore, the high availability of oxygen in the microcirculation, obtained with the O2Hb promotes repair of damaged tissue.
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IN CHRONIC REFRACTORY OSTEOMYELITIS
Some chronic osteomyelitis in the form evolutionary refractory are rebels all forms of treatment, so the disease continues for an indefinite period. Is sometimes little vascularized laminar cortical bone, as in some sectors of the mandible. It can occur as a result of laborious and traumatic extractions, associated with intraosseous pus that is watered by the cancellous bone (trabecular) limited by the cortical. This torpid evolution is due to the adoption of mechanisms of resistance by the respon-sible microroganismo and the ineffectiveness of the natural mechanisms of defense against an inaccessible area, hypoxic and poor or no bioavailability of antibiotics. One of the most important problems is the existence of a barrier-tion between infection and the host intact, which may consist of necrotic bone, oozing, avascular scars, etc. The clinical picture can present with spontaneous purulent vestibular groove, with a diagnostic nuclear medicine box, characterized by an uptake in the study area in three phases. Histological analysis may show chronic inflammatory infiltrate with necrotic bone trabeculae. O2Hb stimulates the permeability of this barrier, promotes fibroblast division and hydroxylation of precolágeno, increasing production of collagen (with increased PO2 between 20 and 30 mmHg), creating the structural basis for angiogenesis, in addition to surgical debridement microscopic osteoclast function produced by the infected or necrotic bone. After 20 sessions O2Hb-tions, histological studies revealed revascularization and formation of healthy bone. In short we can describe the O2Hb acts favorably on the refractory osteomyelitis in the facial area by increasing osteoclast function and osteo-genesis, vascular neoformation, the phagocytic activity of leukocytes, the elimina-tion Direct aerobic and anaerobic bacteria bias, the potentiation effect of aminoglycosides, the mechanisms of host defense, favors processes trización scarring by increasing collagen, reducing local edema and diffusion barrier.
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EFFECT ON OSTEO-radionecrosis
Ionizing radiation affects tumor tissue and healthy tissue. On the soft tissue causes atrophy of the skin, ulcers, on the blood vessel inflammation, degeneration and necrosis of the endothelium, thickening of the endothelium, proliferative vasculitis and necrotizing arteritis. A bone level is no effect on the glass san-guinea and death of bone necrosis. As described in the above concepts, the O2Hb has beneficial effects and proper recovery by raising the PO2 at the cellular level, triggering the cascade of angiogenesis hyperoxia increases the activity of osteoclasts on bone tissue and necrotic osteogenesis.
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EFFECT ON GRAFT
After excision of the graft, blood vessels collapse. The minimum pressure should be 1-2 mm of blood per minute per 100 grams of tissue, whether this low pressure that produces a big amount of free radicals, hypoxia, necrosis and coma sequential myocytes, adipocytes and cells endothelial cells. Moreover, the grafted tissue where it is swollen and it brings destruction of the Na-K, free radicals and increased edema. Contraction of the microcirculation and hypoxia. The benefit is demonstrated by the O2Hb relieving hypoxia, tissue ischemia, promotes microcirculation, decreases platelet aggregation and metabolic disturbances of tissue hypoxia, raising the levels of phosphodiesterase and CPK.
In summary, the effects of O2Hb described above are:
1. Correction of hypoxic tissue states.
2. Stimulation of biosynthetic and reparative processes by stimulating the capillary angiogenesis, proliferation of fibroblasts and collagen synthesis.
3. Osteogenesis modulator process.
4. Potentiates the action of aminoglycosides.
5. Direct bactericidal and bacteriostatic anaerobic bacteria on aerobic.
6. Halts production of alpha toxin by anaerobic bacteria.
7. Synergistic action breaks own infections mixed bacterial flora.
8. Restores the phagocytic capacity of PMN.
9. Hypoxemic vasoconstriction is not favoring the reduction of interstitial edema and extravasation of plasma.
10. Limits the lifetime of COHb.
11. Antiplatelet and anteiserotonínico.
12. Porterior attenuates reperfusion injury to ischemic events.
13. Regulates the function gastroinstetinal promoting peristalsis, decreasing the mechanical effect of the gases, increasing the production of mucus and promoting intestinal absorption.
14. Promotes the synthesis of prostaglandins, steroid hormones and interferon production.
15. Modulator of the immune response.
16. Adjust the sensitivity of the hormone estrogen receptors and mediators.
17. Reducing the effect of mechanical and embolized gas diffusion.
18. Inhibition of leukocyte adhesion to vascular endothelium by modulating the inflammatory response.
19. Correcting tissue hypoxia associated with endoarteritis.
20. Marginal tissue preserved demarcating viable and nonviable.
21. Increases erythrocyte flexibility by encouraging the passage of blood in the microcirculation.
the O2Hb In dentistry can be applied directly to:
1. Traumagenic moderate and severe edema before and after reconstructive surgery or repair, combined with traumatic brain injury.
2. Odontogenic infection with abscess moderate and severe.
3. Post-surgical edema and extensive oral surgery.
4. Post-surgical edema in orthognathic surgery.
5. Osteomyelitis.
6. Osteo-radionecrosis.
7. Extensive grafts: bone and gingival mucous.
8. Tumor resection leaving bloody areas.
9. All acute inflammatory processes by their cost-benefit analysis to justify their use.
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REFERENCES 1. Bert, P. Barometric Pressure. 1879-579. (They are moved by MS and FA Hitchcock) Reprinted by the Underesea Medical Society, Bethesda, 1978.
2. Boerema, I, JA Droll, NG Meijine, E Lokin, B. Kroon and JW Huiskes “High Atmospheric presassure an an aid to cardiac surgery” Arch. Chir. Neerl. 1956; 8:193-211.
3. Boerema, I. Life Whithout blood, J. Cardovasc. Surg. I: 133-146, 1960.
4. Browo RB, Sands M. Infectious disease indications for Hyperbaric oxygen therapy. Compr Ther 1995; 21: 663-7.
5. Browse, NL. The diagnosis an management of primary limphedema. J vasc Surg. 1986:3(1): 181-4.
6. Ciani, P; Williams, C; Leuder, H y cols. Adjunctive Hyperbaric oxigen in the treatment of Thermal Burns. An economic analisis. J. Burn Care Rehabili 1990, 11(2):140-3.
7. Dasilva, et al: Hyperbaric Oxygen (O2 HB) in Conjunction with Traditional Treatment of Troublesome Wounds, Program and Abstracts, 24th International Congress of Internal Medicine, Lima. Nov. 1998; Ps: 012:46.
8. Ald Desola J. Evaluation of the usefulness of O2Hb in Internal Medicine. Casuistry Review 1980-1986 period in Catalunya. Tesca Docloval, University of Barcelona. June 1987.
9. Erick Kidwal: hyperbaric Medicine Practice. Second Edition. Chapters 4, 8, 9. 1995.
10. Folkman J. Angiogenesis In: (Jaffe EA, Ed) Biology of Endothelial Cells. Boston: Martinus Nijhoff Publishers, 1984, 412-428.
11. Grim PS, Gottlieb LJ, Boddie A. Batson E. Hyperbaric oxygen therapy. JAMA 1990 Apr 25; 263(16): 2216-2220.
12. Heng MC, Karker J, Csathy G, Marshall C, Brazier J, Sumampong S, Paterno Gomez E. Angiogenesis in necrotic ulcers treated with Hyperbaric oxygen. Ostomy Wound Manage 2000 Sep; 46(9); 18-28.
13. Krasber –d: Chronic Wound Care: A Clinical Source book for Healthcare Professionals. King of Prussia: Health Management Publications. Inc. 1990.
14. Moreno, M. V. Síndrome de Melkersson-Rosenthal http://www.actamedica.com/vol23-05/a235-061.htm
15. Morrey BF, Dunn JM, Heimbach RD, et al. Hyperbaric oxygen and chronic osteomyelitis. Clin Orthop 1979; 144: 121-7.
16. Nylander, G, Lewis, D; Nordstrom, H & cols. Reduction of post-ischemic edema with Hyperbaric oxygen. Plast Reconstr Surg 1985, 76: 596-601.
17. Silver IA. The measurement of oxygen tensions in healding tissue Prog. Respr.Res. 1969; 3: 124-135.
18. Siddiqui A, Davidson JD, Mustoe TA: Ischemia Tissue Oxigen Capacitance, after Hyperbaric Therapy; A new Physiologic concept; Plast Reconstrur Surg Jan 1997; 99(1): 148-55.
19. Silver IA. Cellular Microenvironment in healing and non-healing wounds. In(Hunt TK Heppenstall RB, Pines E. Roree D. Eds) Soft and Hard Tissue Repair. Biological and Clinical aspects. New York: Praezer Scientific; 1984: 50-66.
Pharmaceutical Calculations Socklosa
Author: Dr. Bada Elvys Perez They scheduled a course of treatment with hyperbaric oxygenation of 15 sessions at 2 ATA, except where ulcerative colitis treatment cycles were scheduled every 3 months. All patients were maintained on conventional treatment had at the time of the investigation.
hyperbaric oxygen proved to be a useful therapeutic alternative and shortened the developmental period of these entities regardless of the use or non-traditional treatment used on them.
INTRODUCTION:
In recent decades, scientific advances have developed many techniques for gastrointestinal diseases the application of molecular methods for the prevention, diagnosis and treatment of these diseases to therapeutic interventions is not radiological and endoscopic surgery, minimal bloody surgery and organ transplants. However, despite these advances, even the cornerstone of medicine is efficient patient care and selection of appropriate therapeutic options. (1, 2, 3.4). Within
digestive diseases frequently are hepatitis etiologies whose main hepatotropic viruses (A, B, C, D, E, G), toxic causes and other diseases that affect less frequently liver parenchyma. In the case of viral hepatitis, caused by the hepatitis B virus remains a major health problem worldwide, evolving with acute and chronic despite immunization policies on risk groups (5, 6.7). Moreover, the hepatitis C is responsible for 50% of cases of chronic hepatitis worldwide, has reported its carcinogenic nature with a high incidence in the susceptible population. (5, 6.8).
Given this wide range of etiologies and clinical, in the case of hepatotropic virus, there is only specific treatment for some forms of hepatitis B and C (interferon alpha and nucleoside analogues). Interferon alpha has been described as a treatment of choice for some clinical forms and the emergence of nucleoside analogues (Ribavirin, Lamivudine) and its combination with the first has allowed different therapeutic regimens have been tested but the overall results are relatively disappointing. For all other etiological forms do not have an effective therapy even in those patients who evolve unfavorably, with the exception of general measures for all critically ill patients. (9,10).
Peptic ulcer is a challenge for medicine due to its high incidence and high cost. Because of this have emerged new diagnostic techniques among which are: various methods for the demonstration of Helicobacter pylori, endoscopic techniques and therapeutic strategies aimed at the eradication of this germ and the restoration of the defense mechanisms of the gastrointestinal tract. Despite these advances in diagnosis and therapy, about 1% of ulcer patients experienced any complications each year so the likelihood of this varies from 20-30% over the natural evolution of the disease, increasing the risk from the time when the first complication occurs. Against this background have launched various schemes treatment, but so far none has shown absolute effectiveness. (11,12).
immune Ulcerative colitis is a chronic inflammatory disorder that evolves with exacerbations and remissions in which up to 10% of patients may develop a fulminant with perforation, massive bleeding, sepsis and toxemia in the initial attack. Therefore we have made many efforts to try to find an effective treatment regimen, but so far remains a chronic, incurable from a medical standpoint. (13,14).
The Hyperbaric Oxygen is breathing pure oxygen (100%) at pressures above normal in an airtight container, which is achieved by the dissolution of additional quantities of the same blood and body fluids under the law of Henry. This law states that the dissolution of a gas (constant temperature) in body fluids is directly proportional to the partial pressure of which is under the same, which is accomplished by a high diffusion gradient of the gas from the blood tissues and provides a reservoir of oxygen bound to hemoglobin. This hyperoxia causes several beneficial effects including: the correction of hypoxia, vasoconstriction without affecting tissue oxygenation, which reduces swelling, stimulates repair processes and scarring, oxygen-dependent bactericidal activity of polymorphonuclear cells and macrophages and promotes the synthesis of natural interferons. (15, 16,17).
Given the variability of the effectiveness of conventional treatment alternatives diseases described above, and based on the beneficial effects of hyperbaric oxygenation decided to use this therapeutic modality for the treatment of these entities.
OBJECTIVES:
General:
1 - Assess the utility of hyperbaric oxygenation in some digestive diseases such as acute hepatitis complicated peptic ulcer and ulcerative colitis immune.
Specific:
1 -. To determine the clinical and laboratory examinations of each pathology.
2 -. Compare the results of treatment with hyperbaric oxygenation when used as single therapy with those obtained when it is combined with conventional treatment.
3 -. Analyze the costs of treatment.
MATERIAL AND METHODS:
were treated at University Hospital "Celestino Hernandez Robau" of Santa Clara in the period from January 200 to December 2006 a total of 198 patients with the following criteria:
1 - . Acute viral hepatitis torpid evidenced by:
a) clinical and humoral signs of liver failure.
b) Cholestasis of two months or more without improving trend.
c) Persistence of enzymatic alterations with no tendency to normalization after three months.
2 -. Duodenal ulcer refractory to conventional treatment or complications during her debut.
3 -. Gastric ulcer.
4 -. Ulcerative colitis with acute diarrheal immune at the time of the study or frequent.
Patients with acute hepatitis underwent glutamic pyruvic transaminase (GPT) and total bilirubin (if jaundice) initiation of treatment with hyperbaric oxygenation) in the 8th session and at the end of it. To analyze the behavior of these numbers in graphs, are found the average value at each time of treatment. Was also carried surface antigen for HBV and HCV antibody before and during the treatment regimen in order to classify serologically liver disease. Seronegative hepatitis were considered those that did not correspond to these viruses. Among other causes were considered particularly toxic.
All patients with peptic ulcers were diagnosed endoscopically (they did Histological all gastric ulcers) and this test was repeated 10 to 15 days after completion of the last session.
Patients suffering from ulcerative colitis were diagnosed immune endoscopic and histological and radiological study was performed were the colon when it was relevant.
All patients were maintained on treatment for each disease if they had, except for patients with ulcerative colitis under treatment with steroids, which was suspended or reduced to minimum dose. They scheduled a course of treatment with hyperbaric oxygenation in a daily session from Monday through Friday, except in patients with liver failure which provided 2 sessions of treatment per day and in the case of patients with ulcerative colitis where treatment cycles were scheduled every three months. There were a total of fifteen sessions. The teams were compressed to 2 atmospheres absolute pressure (ATA) for 50 minutes isopressure (1 hour in liver failure) with fast compression and decompression of 0.1-0.2 FGR x cm2 x min. The treatment was done in Soviet-made car cameras.
The course of treatment effectiveness was assessed according to criteria of the National Hyperbaric Medicine:
A) Satisfactory resolution and clinical examinations laboratory.
B) Regular: no objective clinical improvement confirmed by laboratory tests.
C) Not satisfactory: No clinical response or additional. To
effectiveness analysis took into account the cases assessed as satisfactory.
Results and presented in tables and graphs from the statistical point of view applied the Mantel-Hanzel method in order to determine whether there were significant differences between treatment effects loe (Hyperbaric oxygen with or without conventional treatment) adjusted for clinical forms. The research was conducted with a significance level of 5% in case there Significant differences were calculated adjusted relative risk.
RESULTS AND DISCUSSION
Table No. 1 shows the distribution of patients by sex and average age in the different pathologies studied. The mean age was 35.6 years, being higher that of those patients with gastric ulcer 48.4 years. There was a predominance of males (69.5%), more evident in the duodenal ulcer (77%) and acute hepatitis (73.7%)
The average age of our sample corresponds with what was expected because it is diseases predominantly affecting young adults, except for gastric ulcer which are reported in later ages. This predominance of old evidence that this research focused on a socially active population group in which the cure or shorten the course of the disease of great economic and social importance.
tabal In No. 2 we can observe the distribution of clinical and etiological forms of acute hepatitis. The total (110), 71 corresponded to seronegative hepatitis, second hepatitis B are the number of 30 (27.3%), while the most frequent clinical forms was extended to 57 patients (51.8%) followed by the colostásica with 45 (40.9%).
Figures 1 and 2 shows the evolution of the total bilurribina tgp and in acute hepatitis. Each curve represents the clinical forms. The decrease was significant figures and bilirubin tgp how long. The reduction of the average values \u200b\u200bof tgp and bilirubin was evident from the second sampling, which corresponded with clinical improvement in patients who had 3 or more months with no tendency to improve clinical and humoral.
This positive development can be attributed to some of the effects of hyperbaric oxygenation on liver parenchyma in the literature. Hyperbaric oxygen restores the tissue levels of this gas in the liver inflamed, reduces edema secondary to inflammation due to physiological hyperoxic vasoconstriction without affecting tissue oxygenation due to the high levels of dissolved oxygen in the blood (3 times higher than normal). This leads to an improvement in microcirculation. Also described a stimulation in hepatic lipid detoxification capacity, and an increase in the synthesis of natural interferons. This sum of effects results in a restoration of liver function (15, 16,17).
Treatment outcomes for each clinical form described in Table 3 in which we can see that there were positive results (92.8% and 100%) for hepatitis colostasicas prolonged evolution, respectively, while in patients with well-developed liver failure 75% of them. 99% of patients who used hyperbaric oxygen therapy alone responded favorably while 80% of those who used combined with interferon showed satisfactory results. Statistical analysis showed that for each clinical form significant differences (X2 = 6.4580) between both treatment groups and frequency of treatment failure associated with interferon Hyperbaric oxygen is greater than when it is used alone. overall effectiveness of both treatment groups was 97.3%
In our study, the Hyperbaric Oxygen demonstrated efficacy in the management of patients with acute hepatitis torpid, regardless of etiology and although there were significant differences between treatment groups think that this might be influenced by the smallest number of patients treated with the combination of interferon and Hyperbaric Oxygen. Moreover, most of these cases involved patients with acute hepatitis B or C is known tend to evolve less favorable. Hyperbaric Oxygenation with or without interferon shortened the developmental period of acute hepatitis independence its etiology.
predisposing factors, the duration of symptoms and complications of peptic ulcer are shown in Table 4. The median time to progression was 59.4 months (4.95 years) and 87% of patients had a predisposing factor. 77% of them had previous complications or the debut. Most of these patients (84.4%) had duodenal ulcer and 14.3% in the stomach.
toxic habits such as smoking, alcohol consumption, coffee, ulcerogenic drugs, as the profession itself were evaluated as predisposing factors. The behavior of those in the sample was studied as described in the literature.
Nearly half of patients with duodenal ulcer debuted or had complications, mostly gastrointestinal bleeding in one case there was a pre-drilling and 3 of them had undergone surgery.
The results of treatment of different types of ulcer and ulcerative colitis are immune shown in Table 5. In the case of peptic ulcer overall effectiveness of treatment was 80.5% highlighting the results of gastric ulcer (90.9%), followed by duodenal (78.5%). All gastric ulcers treated with combination therapy. 75% of duodenal ulcer patients treated with conventional therapy Hyperbaric oxygen and a favorable outcome, while 92.3% of patients in the hyperbaric chamber which was used as a single treatment, the ulcer healed.
90.9% of patients with ulcerative colitis showed clinical remission immune evident.
Statistical analysis showed no significant differences between treatment groups in the case of peptic ulcer disease for each clinical form and the immune ulcerative colitis. (X2 = 3.21).
There are many schemes for ulcer treatment ulcer and also provides diagnostic and novel techniques that have enabled a step forward in the diagnosis and treatment of the entity. The cure rates of these ranges between 77 and 91% (2, 18,19)
The beneficial effects of hyperbaric oxygen on the ulcers are due to an injury is hypoxic colitis, a fact that the camera is corrected also stimulates the healing by fibroblast proliferation and increased synthesis of collagen, increases the oxygen-dependent bactericidal activity of macrophages polimorfonicleares and also their likely effect on the growth of Helicobacter pylori is a microaerophilic germ. (15, 16,17).
immune Ulcerative colitis is a disease difficult to treat because a low percentage of patients presents with a single attack without recurrence. In his treatment have been tried several schemes of drugs and surgical techniques. (20).
In our series showed the hyperbaric chamber effective when associated or not to conventional treatment of this entity, being remarkable that at one year 90.9% of patients had presented no clinical relapse after several courses of treatment. This result is attributed to its beneficial effect on wound healing reduction of edema and stimulation wing of the synthesis of natural interferons (15, 16,17)
Table 6 shows the costs of treatment used compared with conventional treatment, bearing in mind that our study showed that in 2 pathology represented no significant differences between treatment groups in both the Hyperbaric Oxygen is a cheaper alternative, you should consider this approach for the treatment of these entities
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Dr. Alejandro García Rodríguez, president of the Mexican Association of Hyperbaric Oxygen and Cell Regeneration, explained that oxygen therapy prevents adverse environmental conditions and stress accelerate the processes degenerative cells. So
normal cells in our body uses 21% of oxygen is taken, but in polluted cities such as Mexico, that percentage drops to 18%.
in hyperbaric chambers, breathing the chemical in high atmospheric pressure conditions, the body is oxygenated to 20 times more and this creates great physical and psychological benefits.
The specialist explains that this therapy is not only suitable for those suffering from certain disease, but can be used by those wishing to revitalize their bodies, their skin tone and boost your immune system. This ultimately contributes to disease prevention and improve the quality of life. Hyperbaric oxygen therapy
This technique is applied in a pressurized metal chamber, which can be sitting or lying down. The person stays there for an hour, during which inhaled oxygen through a mask.
step process
The first thing the patient to reach the center of oxygen is to register and provide their data, so that you make your medical history and from this, decide if it is safe or not receiving hyperbaric oxygen therapy.
"After the assessment, depending on individual needs, will decide at what pressure the camera is placed and the number of sessions required by the person, "says Carlos Collado.
10 are generally recommended to begin with.
If women are instructed to present themselves without makeup or accessories metal, and dress in cotton or disposable items (the latter is provided at the clinic). "
them and male patients are asked during the session turn off the phone. "For the therapy has the desired effect, it requires concentration." said Dr. Collado.
The hyperbaric chamber is a device that injects air into the interior, producing an increase in pressure; This makes oxygen readily dissolves in the blood, he added.
In some cases, prior to entry into the chamber, the patient receives a massage, a therapist or talk with him, to help de-stress. Technical
safe
Although it is known that for many years used hyperbaric chambers, it was not until the 60's when they started using so much as they do today.
Although there are very few specialists in the medical industry in the world, the use of hyperbaric chambers is approved by the FDA (Food & Drugs Administration) and the AMA (American Medical Association) in the United States and other institutions in Russia, Cuba and countries of Europe, Asia and South America. In Mexico, is supported by the Instituto Mexicano del Seguro Social, ISSSTE and other official institutions of government. Risk-free
Hyperbaric chambers can use them from children to seniors.
restrictions are for people with severe pulmonary emphysema, trauma (punctures) of the lung, claustrophobia, and some specific heart disease.